Publications

Publications since 2005

  • Haro E, Petit F, Pira CU, Spady CD, Ivey LA, Gray AL, Escande F, Jourdain A-F, Nguyen A, Fellmann F, Good J-M, Francannet C, Manouvrier-Hanu S, Ros MA, Oberg KC (2020) Identification of limb-specific Lmx1b auto-regulatory modules with Nail-Patella Syndrome pathogenicity. Nat Commun. [bioRxiv]
  • Fernandez-Guerrero M, Yakushiji-Kaminatsui N, Lopez-Delisle L, Zdral S, Darbellay F, Perez-Gomez E, Bolt CC, Sanchez-Martin MA, Duboule D, Ros MA (2020). Specific ectodermal enhancers control the expression of Hoxc genes in developing mammalina integuments. Proc Natl Acad Sci US. [bioRxiv]
  • Pérez-Gómez, Fernández-Guerrero M, Campa V, Lopez-Gimenez JF, Rada-Iglesias A and Ros MA (2020). Sp8 regulatory function in the limb bud ectoderm. Elife submitted. [bioRxiv]
  • Busby L, Aceituno C, McQueen C, Rich CA, Ros MA, Towers M. Sonic hedgehog specifies flight feather positional information in avian wings. Development. 2020;147(9):dev188821. [PubMed]
  • Role of Hox genes in regulating digit patterning.  Pérez-Gómez R, Haro E, Fernández-Guerrero M, Bastida MF, Ros MA.  Int J Dev Biol. 2018;62(11-12):797-805. [PubMed]
  • An intrinsic cell cycle timer terminates limb bud outgrowth.  Pickering J, Rich CA, Stainton H, Aceituno C, Chinnaiya K, Saiz-Lopez P, Ros MA, Towers M. Elife. 2018 Sep 3;7. pii: e37429. doi: 10.7554/eLife.37429. [PubMed]
  • Intrinsic properties of limb bud cells can be differentially reset.Saiz-Lopez P, Chinnaiya K, Towers M, Ros MA. Development. 2017 Feb 1;144(3):479-486. [PubMed]
  • Ectoderm-mesoderm crosstalk in the embryonic limb: The role of fibroblast growth factor signaling.Mariani FV, Fernandez-Teran M, Ros MA. Dev Dyn. 2017 Apr;246(4):208-216. [PubMed]
  • CathepsinKCre mediated deletion of βcatenin results in dramatic loss of bone mass by targeting both osteoclasts and osteoblastic cells. Ruiz P, Martin-Millan M, Gonzalez-Martin MC, Almeida M, González-Macias J, Ros MA. Sci Rep. 2016 Nov 2;6:36201. [PubMed]
  • HOX13 proteins: the molecular switcher in Hoxd bimodal regulation. Ros MA. Genes Dev. 2016 May 15;30(10):1135-7. doi: 10.1101/gad.283598.116. [PubMed]
  • An intrinsic timer specifies distal structures of the vertebrate limb. Saiz-Lopez P, Chinnaiya K, Campa VM, Delgado I, Ros MA, Towers M. Nat Commun. 2015 Sep 18;6:8108. [PubMed]
  • Sp6 and Sp8 Transcription Factors Control AER Formation and Dorsal-Ventral Patterning in Limb Development. Haro E, Delgado I, Junco M, Yamada Y, Mansouri A, Oberg KC, Ros MA. PLoS Genet. 2014 Aug 28;10(8):e1004468. [PubMed]
  • Long bone development requires a threshold of Hox function. González-Martín MC, Mallo M, Ros MA. Dev Biol. 2014 Aug 15;392(2):454-65. [PubMed]
  • Forward to the special issue on Hox/Tale transcription factors in development and disease. Wellik DM, Torres M, Ros MA. Dev Dyn. 2014 Jan;243(1):1-3. doi: 10.1002/dvdy.24098. Epub 2013 Dec 9. [PubMed]
  • Evidence that the limb bud ectoderm is required for survival of the underlying mesoderm. Fernandez-Teran M, Ros MA, Mariani FV. Dev Biol. 2013 Sep 15;381(2):341-52. [PubMed]
  • Decoupling the function of Hox and Shh in developing limb reveals multiple inputs of Hox genes on limb growth. Sheth R, Grégoire D, Dumouchel A, Scotti M, Pham JM, Nemec S, Bastida MF, Ros MA, Kmita M. Development. 2013 May;140(10):2130-8. doi: 10.1242/dev.089409. [PubMed]
  • Sheth R, Bastida MF, Kmita M, Ros M. (2014). «Self-regulation», a new facet of Hox genes’ function. Dev Dyn. 2014 Jan; 243(1): 182-91.
  • Fernandez-Teran M, Ros MA, Mariani FV (2013). Evidence that the limb bud ectoderm is required for survival of the underlying mesoderm. Dev Biol. 2013 Sep 15;381(2):341-52
  • Sheth R, Grégoire D, Dumouchel A, Scotti M, Pham JM, Nemec S, Bastida MF, Ros MA, Kmita M. (2013). Decoupling the function of Hox and Shh in developing limb reveals multiple inputs of Hox genes on limb growth. Development. 2013 May; 140(10):2130-8.
  • Sheth R, Marcon L, Bastida MF, Junco M, Quintana L, Dahn R, Kmita M, Sharpe J, Ros MA. (2012) Hox genes regulate digit patterning by controlling the wavelength of a Turing-type mechanism. Science. 2012 Dec 14;338(6113): 1476-80.
  • Garrido-Allepuz C, González-Lamuño D, Ros MA. (2012) Sirenomelia phenotype in bmp7;shh compound mutants: a novel experimental model for studies of caudal body malformations. PLoS One. 2012;7(9):e44962.
  • R​oselló-Díez A., Ros M.A. and Torres M. (2011). Diffusible signals, not autonomous mechanisms determine the main proximodistal limb subdivision. Science.2011; 332:1086-1088.
  • Cooper K.L.,  Hu J K-H, Berge D., Fernandez-Teran M, Ros M.A. and Tabin C.J.  (2011). Proximal-distal patterning of the vertebrate limb is initiated by altered exposure to secreted signals. Science,
  • Garrido-Allepuz, C., Haro, E., Gonzalez-Lamuño, D., Martinez-Frías, M.L., Bertocchini, F. and Ros M.A. (2011) Sirenomelia: A Clinical and Experimental Review. Disease Models and Mechanism, Talamillo, A., Delgado, I., Nakamura, T., De-Vega S., Yoshitomi Y, Unda F, Birchmeier W, Hamada, Y., Ros, M.A. (2010).  Role of epiprofin, azinc-finger transcription factor, in limb development.  Developmental Biology 337,
  • Galoway, J.L., Delgado, I., Ros, M.A. and Tabin, C.J. (2009). A Reevaluation of X-Irradiation Induced Phocomelia and Proximodistal Limb Patterning. Nature 60:400-404.
  • Dominguez-Frutos, E., Vendrel, V., Alvarez, Y., Zelarayan, L.C., Lopez-Herandez, I., Ros, M., Schimmang, T. (2009). Tissue-specific requirements for FGF8 during early inner ear development. Mechanisms of Development 126:873-881.
  • Alvarez-Medina R., Le Dreau G., Ros M., Marti, E. (2009) Hedgehog activation is required upstream of Wnt signalling to control neural progenitor proliferation. Development 136: 3301- 3309.
  • Bastida, M.F., Sheth, R. and Ros, M.A. (2009) A Bmp/Shh negative feedback loop serves to restrict Shh expresion during limb development. Development 136: 3779- 3789.